Examine with your medical medical doctor or dentist in advance of having any of the above mentioned if you are taking this medicine.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people below 6 years of age, because The mix could trigger lethal respiratory depression During this age populace. It's important that promethazine with codeine syrup is calculated with an accurate measuring product (see Safety measures-Details For Sufferers).
Some side effects may possibly manifest that typically usually do not will need professional medical attention. These Unwanted side effects might disappear for the duration of therapy as your body adjusts on the medication. Also, your overall health treatment Qualified may be able to show you about means to avoid or cut down Some Unwanted effects.
When medical professionals prescribe codeine-made up of medications, they must choose the most affordable helpful dose for your shortest timeframe and may advise their individuals about these pitfalls and the signs of morphine overdose (see PRECAUTIONS - Nursing Mothers).
Employing this medication with any of the following medicines may trigger an elevated hazard of certain Unintended effects, but utilizing both prescription drugs often is the finest procedure for yourself. If equally medicines are prescribed collectively, your doctor may alter the dose or how often you use one or each of your medicines.
The causal job of opioids while in the clinical syndrome of hypogonadism is unknown since the different clinical, Bodily, Way of living, and psychological stressors that could influence gonadal hormone levels have not been sufficiently controlled for in scientific tests performed so far [see ADVERSE REACTIONS (six)].
Stay away from the use of Promethazine with Codeine Oral Solution in individuals taking muscle mass relaxants. If concomitant use is critical, watch people for indications of respiratory melancholy Which may be higher than in any other case anticipated.
It really is soluble in drinking water and freely soluble in alcohol. It has website a molecular excess weight of 320.88, a molecular formulation of C17H20N2S•HCI, and the following structural formula:
However, If the mouth continues to experience dry for a lot more than 2 months, Check out with your professional medical physician or dentist. Continuing dryness of the mouth may perhaps raise the probability of dental illness, together with tooth decay, gum condition, and fungus bacterial infections .
It truly is tough to figure out what constitutes an ordinary poisonous or lethal dose. Nonetheless, the lethal oral dose of codeine within an adult is claimed to get inside the selection of 0.
Cardiovascular: Check for signs of hypotension, specifically in All those whose blood pressure level is compromised
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Lengthy-term animal scientific tests haven't been executed to evaluate the carcinogenic likely of codeine or of promethazine, nor are there other animal or human data concerning carcinogenicity, mutagenicity, or impairment of fertility with these brokers.
Choose this medication particularly as prescribed to decrease the risk of dependancy. Question your medical doctor or pharmacist for more facts.